Darkfield microscopy
Our blood carries bacterial DNA!
Researchers have observed so-called pleomorphic bacteria, including the spirochetes implicated in Alzheimer's disease, in the blood of healthy human subjects, using dark-field microscopy. This was a surprising discovery, since it is generally accepted that the bloodstream in healthy humans is a sterile environment, except in cases of violation of tissue membrane integrity, such as intestinal permeability. However, the concept of the presence of bacteria in the blood of healthy humans is now more plausible thanks to culture-independent laboratory approaches.
Using PCR and FISH techniques, the researchers were able to demonstrate that the blood of clinically healthy human subjects contains bacterial DNA. PCR of the 16S rRNA gene has been widely used to identify uncultivable bacteria in the environment.
Dark field, dark field smear and coagulated blood techniques are used in every consultation, both in the office and remotely.
Years ago, bacterial rDNA sequences were associated with blood, and researchers at the time described intraerythrocytic parasites (inside red blood cells) in clinically healthy human subjects. Today, we know that intraerythrocytic DNA is associated with bacterial presence.
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